Large amounts of weight gain in adulthood increase the risk for endometrial cancer two-fold, new research shows.

The American Cancer Society collected data from 38,000 postmenopausal women with an intact uterus including 560 with endometrial cancer. There was an almost fourfold risk in women who gained 61 pounds or more over 15 years compared with those whose weight remained stable.

After adjusting for baseline BMI, this translated to a twofold increased risk for the cancer from weight gain, but yo-yo dieting did not increase risk.

Findings were reported at the 10^th American Association for Cancer Research International Conference on Frontiers in Cancer Prevention.

http://www.aacr.org/home/public--media/aacr-press-releases.aspx?d=2514

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Content updated November 2011