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IMS Menopause Live

Oncology in midlife and beyond

To mark World Menopause Day on 18th October, the International Menopause Society has published a major review of cancer during and after the menopause, and asks women and their doctors to take appropriate precautions to minimise cancer risk.

Full Paper

Gompel A, Baber RJ, de Villiers TJ, Huang KE, Santen RJ, Shah D, Villaseca P, Shapiro S. Oncology in midlife and beyond. Climacteric. 2013 Oct;16(5):522-35. doi: 10.3109/13697137.2013.823539. Epub 2013 Aug 9.

pdfOncology in midlife and beyond - (personal use only)298.78 KB


The onset of the menopause is often a time when women’s concerns can act as a powerful trigger to encourage healthy modifi cations in lifestyle which will maintain, or improve, their general health. This document aims to help women to understand their potential risks, to encourage them to fi nd proactive preventive strategies by modifying some of their attitudes, and to use health resources (when available) to be screened.

Cancer is an important cause of death but not the primary cause of mortality. Cardio/circulatory diseases represent 35 – 40% of causes of death in most developed countries and 20 – 25% of women will die from cancers in Western Europe, Australasia, high-income North America, high-income Asia Pacific, East Asia and Southern Latin America. Breast cancer, lung cancer and colorectal cancer are prevalent in most regions of the world. Cervical cancer remains a hallmark of low access to health care. Preventive strategies (decreasing smoking and alcohol consumption, losing weight, eating a healthy diet and undertaking physical activity) and implementation of screening could help to signifi cantly decrease the incidence of and mortality from cancer. The mortality/incidence ratio is higher in developing countries compared to high-income regions as well as in subgroups of populations in developed countries with lower socioeconomic levels.

Implementation of better diagnostic methods and management of cancer according to the local resources will help to decrease the mortality rate in developing countries, and effort has to be made to decrease social inequities and improve access to health care for low-income groups. In conclusion, cancer incidence is increasing as a consequence of longer life expectancy all over the world. National health programs are mandatory to implement screening and to improve individual management.

Finally, educating women so that they are aware of ways to improve their general health, to minimize their own risk factors and to identify signs of change in their own health which may be markers of impending cancer will help to reduce the burden of disease and improve the prognosis for tumors detected at an earlier stage.

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