Menopausal Hormone Therapy (MHT) discontinuation and shortages September 2025
Menopausal Hormone Therapy (MHT) discontinuation and shortages September 2025
Australia
Patch Shortages
There are a number of MHTs that are currently unavailable. Please note that the TGA has approved some unregistered products under Section 19A and some substitute doses are currently in supply in Australia. Pharmacists are encouraged to contact suppliers Medsurge Healthcare Pty Ltd on 1300 788 261 for orders of Estramon, and Sandoz on 1800 726 369 for orders of Estradiol Transdermal System.
Oestradiol patches
Availability and expected supply due |
Alternative supply under Section 19A |
|||
Dose |
Estradot |
Estraderm |
Estramon |
Estradiol Transdermal System |
25 mcg |
Unavailable -31st Dec 2025 |
Available |
Available |
|
37.5 mcg |
Available |
|||
50 mcg |
Unavailable -31st Dec 2025 |
Available |
Available |
|
75 mcg |
Unavailable -31st Dec 2025 |
Unavailable– 10th October 2025 |
Available |
|
100 mcg |
Unavailable -31st Dec 2025 |
Unavailable – 10th October 2025 |
Available |
Please note: The temporary replacement of Estradot (due to shortage), which was Estradiol Transdermal System (temporarily supplementing this shortage) has now been used up. From next month Estradiol Transdermal System will be removed from the table.
Combined patches
Dose |
Estalis Sequi |
Estalis Conti |
50/140 |
Unavailable – 17th Oct 2025 |
Available |
50/250 |
Available |
Available |
All doses of Climara have been deleted from the market and there will be a reduction in supply until supply is exhausted.
The AMS Guide to MHT Doses (Australia only) provides a guideline to approximately equivalent doses of the different MHT/HRT products in Australia.
New Zealand
As at 25th September, patch availability is provided below.
Dose |
Estradot |
Viatris |
25mcg |
Available |
Unavailable |
50mcg |
Available |
Unavailable |
75mcg |
Available |
Unavailable |
100mcg |
Available |
Unavailable |
More information can be found at https://pharmac.govt.nz/medicine-funding-and-supply/medicine-notices/oestradiol/?mType=all
The AMS Guide to MHT Doses (New Zealand only) provides a guideline to approximately equivalent doses of the different MHT/HRT products in New Zealand.