About the study

Blood vessel function declines with age and often precedes cardiovascular disease (CVD). Hormonal changes during menopause may also further contribute to vascular dysfunction and CVD risk in females.

While it is well-established that exercise training can reduce CVD risk, it is currently unclear if initiating exercise training pre menopause is more effective at improving vascular function than post-menopause.

The Lifelong Exercise and vAscular function in Females (LEAF) study is looking at how cardiovascular function changes in females throughout the lifespan and how exercise training may improve age and menopause-related declines in vascular function.

The population of interest for this trial are post-menopausal females aged 50 – 60 years old and pre-menopausal females aged 45-55 with a BMI ≤ 30, that are either ‘exercise trained’ or ‘physically inactive’.

Researchers

A/Prof Erin Howden, Dr Jack Talbot, Dr Sarah Alexander, Dr Leah Wright, Dr Kegan Moneghetti

Ethics Approval

This study has been approved by the Alfred Health Human Research Ethics Committee. HREC Approval No: 114169.

LEAF Study ETHICS APPROVAL CERTIFICATE133.83 KB

Contact

Dr Jack Talbot This email address is being protected from spambots. You need JavaScript enabled to view it.

https://www.baker.edu.au/research/clinical-trials/leaf-study

Lifelong Exercise training and vAscular function in Females The LEAF Study Flyer127.24 KB

About the study

This study investigates if almond protein improves muscle, fitness, and metabolic health in overweight or obese postmenopausal women during 10 weeks of supervised exercise. Participants consume almond protein or a placebo. Assessments include strength, body composition, and glucose levels. A $100 voucher is provided upon completing the study.

Researchers

Principal Researcher: Dr D. Lee Hamilton

Student Researcher: Vy Tran (PhD student)

Associate Researcher(s): Dr Charles Urwin, Dr Jackson Fyfe, Dr Simon Feros, Dr Gavin Abbott, Dr Sze Yen Tan, Prof Clinton Bruce, Dr Giselle Allsopp, Dr Greg Kowalski, Assoc. Prof Michael Tieland, Dr Rhiannon Snipe, Dr Shaun Mason, Dr Zoya Huschtscha

Ethics approval

This study has been approved by the Deakin University Human Ethics Committee: 2024/HE000126.

Contact

Vy Tran

This email address is being protected from spambots. You need JavaScript enabled to view it.

Flyer: Almond ProFit Study Flyer Update)286.40 KB

Ethics approval: Human Research Ethics Amendment Approval80.69 KB

Plain language summary:  Plain Language Statement339.46 KB

Link to eligibility questionnaire:  https://redcap.deakin.edu.au/surveys/?s=7N3XWHYYN7XTCJN8

About the study

As females enter menopause, blood vessel function can begin to decline due to a reduction in hormone levels in the body. This study aims to identify the effects of high intensity interval training (HIIT) and moderate intensity interval training (MIIT) on preserving blood vessel function in the brain and throughout the body during menopausal transition.

Researchers

Ms Alice Lester, Dr Bert Bond, Mr Conan Shing, Professor Jeff Coombes, Professor Kerrie Moreau, Ms Taela Fonternel, Mr Thomas Kelaart, Dr Jenna Taylor (Centre for Research on Exercise, Physical Activity and Health - The University of Queensland).

Ethics approval

This study has been approved by the University of Queensland Human Research Ethics Committee A. HREC Approval No: 2024/HE001370.

Contact

Conan Shing: This email address is being protected from spambots. You need JavaScript enabled to view it. 

Flyer: PERI-VASC_Partcipant_Recruitment_Flyer_FINAL.pdf2.31 MB

Ethics approval: PER-VASC_Decision_notification_letter151.82 KB

Link to recruitment site: Effect of Exercise Training Intensity on Brain and Body Blood Vessel Function During Perimenopause (The PERI-VASC Study) - Faculty of Health and Behavioural Sciences - University of Queensland

About the study

Women are at higher risk of developing oral health problems during menopause. These oral health problems can significantly affect their quality of life. However, there is currently limited evidence on the oral health knowledge, attitudes, and practices of women in perimenopause/menopause worldwide. Providing appropriate assistance during the early period of the menopausal transition could potentially reduce the prevalence of oral health problems in the perimenopausal/menopausal period and improve overall well-being in the later years.

We invite you to participate in our study (involving a survey and/or interview) which aims to explore your experience regarding oral healthcare and identify challenges in this area. The information you provide will help us identify future strategies and services that could improve oral healthcare for women in perimenopause or menopause. Participation is voluntary and the information you provide will be strictly confidential. You will be reimbursed for your time participating in an interview.

Researchers

Australian Centre for Integration of Oral health (ACIOH), Western Sydney University.

Ethics approval

This study has been approved by the Western Sydney University Human Research Ethics Committee. HREC Approval No: H15712

ACIOH H15712 - Human Ethics Approval40.90 KB

Contact

Namitha Thomas (Chief investigator and PhD student),

Tel: +61 2 8738 9367, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Please click here for participating in a survey: Survey flyer

Please click here for participating in an interview: Interview flyer505.16 KB

About the study: 

Menopause occurs on average at the age of 51 years. By this time women do not produce sufficient estrogen or testosterone necessary for good bone health. As a result, most women experience progressive bone loss, increasing the risk of osteoporosis (weakened bone strength) and fragility fracture.›

Despite adequate estrogen replacement many women also experience loss of sexual desire and arousal after menopause.

There is some evidence that the addition of testosterone to estrogen replacement therapy might prevent bone loss and restore sexual function in women with early menopause, but further evidence from well conducted trials is still needed.

We invite you to participate in this study to determine whether a testosterone therapy approved for use in women in Australia prevents bone loss and improves sexual function in postmenopausal women, aged less than 55 years who are using estrogen replacement.

Participation involves up to 5 visits over 12 months with blood collection, and bone density scans at commencement and at 12 months

Researchers 

Women’s Health Research Program, Monash University

Ethics Approval

This study is approved by Monash University Human Research  Ethics Committee

Contact

To participate or for further information
Please contact:
Women’s Health Research Program
Monash University
Phone: (03) 99030827
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
The Women’s Health Research Program

Monash Study flyer 9.1.2023118.06 KB

[Ref: V 3 dated 9/1/2023]